Fera Science's Advanced Simulation Capabilities
"Our approach is to not only support risk assessors and managers but also deploy Fera's superior analytical capability and metabolism knowledge to deliver efficient transformation screens to understand potential tTPs of interest."
Environmental fate studies are a fundamental part of chemical risk assessment, but there are subtle
differences between how different agencies assess safety. The REACH regulations of the European
Chemical Agency (ECHA) take a more conservative approach to non-extractable residues compared to
other agencies.
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Unlocking Insights in Water Treatment: Fera Science's Advanced Simulation Capabilities
In the dynamic landscape of contaminates within wastewater, understanding the impact of EU waste treatment to ensure safety of active substances and environmental transformation products (eTPs) is paramount. Fera Science proudly announces its investment and expertise in conducting simulation tests, aimed at identifying potential transformation products (tTPs) that emerge during water treatment processes.
Addressing Regulatory Requirements
Guided by the EFSA framework, our rigorous experimental procedures focus on assessing the impact of water treatment on residues of active substances and their metabolites. Our approach is to not only support risk assessors and managers but also deploy Fera's superior analytical capability and metabolism knowledge to deliver efficient transformation screens to understand potential tTPs of interest.
High-Concentration Experiments: Probing Transformation
At Fera Science, our experimental protocols begin with high-concentration tests designed to detect and identify TPs that may form during water treatment. Using methodologies such as chlorination with NaOCl, chloramination, ozone oxidation, UV disinfection, and biodegradation via sand filtration, we delve deep into understanding the chemical transformations at play.
Methodological Rigor and Innovation
Our methods involve meticulous preparation and execution:
⚛️ High-concentration simulation tests using Standard Water C follow by subsequent tests at predicted environmental concentrations.
⚛️ Chlorination with NaOCl: Investigating TPs formed under varying pH conditions to ensure comprehensive coverage.
⚛️ Chloramination: Exploring the effects of NH2Cl in water treatment, highlighting the formation of tTPs under controlled conditions.
⚛️ Pre-oxidation process via Chlorine dioxide.
⚛️ Combination screen using pre-oxidation with ClO2 followed by chlorination with NaClO.
⚛️ Ozonation: Using DBD Ozone generation to uncover potential tTPs.
⚛️ UV Disinfection: Employing precise UV dosages via PearlBeam™ to simulate real-world conditions, crucial for understanding tTPs formed.
⚛️ Biodegradation: In the absence of biotransformation data, Fera science deploys an OECD 314 (B) mimicking natural filtration processes to observe microbial interactions, providing insights into potential TPs in sand filtration.
Advanced Capabilities
Our approach integrates state-of-the-art analytical tools including LC-MS, HPLC-UV-βRAM and GC-MS, facilitating suspect and non-target screening to identify even trace levels of tTPs. This capability ensures that potential health risks associated with these substances are thoroughly evaluated and managed.
Commitment to Environmental Safety
By conducting experiments at both high and environmentally relevant concentrations, we ensure comprehensive coverage of potential tTPs and advancing scientific understanding.
Partner with Fera Science
Whether you're navigating the complexities of regulatory compliance or advancing scientific research, Fera Science stands ready to support your journey. Trust us to deliver insightful, actionable data that safeguards public health and environmental integrity.
For more information on our simulation capabilities and how we can support your projects, visit Fera Science today.
About Fera Science: Fera Science is a leading provider of scientific expertise and analytical services, specialising in agricultural, food and environmental sciences. With a commitment to innovation and regulatory excellence, Fera Science empowers clients globally to make informed decisions and achieve their goals responsibly.